peptide 257 OVA (257-264 - Peptidecatalog OVA 257-264 (SIINFEKL Understanding Peptide 257: An In-Depth Look at OVA Peptide (257-264)

Peptidelist The term "peptide 257" often refers to a specific and highly studied peptide fragment derived from ovalbumin (OVA), a major protein found in egg white.OVA peptide - MedchemExpress.com This particular peptide, known as OVA Peptide (257-264), plays a significant role in immunological research due to its function as a class I (Kb)-restricted peptide epitope of OVA. Understanding this peptide requires delving into its structure, presentation, and applications in scientific investigationsOVA Peptide(257-264) TFAis a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, ....

The Structure and Presentation of OVA Peptide (257-264)

OVA Peptide (257-264) is an octameric peptide, meaning it is composed of eight amino acidsThis is aclass I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.. Its specific sequence is SIINFEKL. This sequence is not arbitrary; it represents a crucial part of the ovalbumin protein that is recognized by the immune system, specifically by T cells.

The presentation of this peptide to the immune system is mediated by MHC class I molecules. In particular, OVA Peptide (257-264) is presented by the H-2Kb molecule, which is a specific type of class I MHC molecule.Ova peptide (257-264) | C45H74N10O13 | CID 22134157 - structure, chemical names, physical and chemical properties, classification, patents, literature, ... This binding to H-2Kb is what makes it a class I (Kb)-restricted peptide epitope.2025年2月17日—这是一种八聚体短肽，属于线性结构，通过肽键连接八个氨基酸。分子整体存在一定的空间构象，能够与MHC I 类分子H-2Kb 的特定部位进行特异性结合，结合区域主要 ... This restriction is vital because it dictates which immune cells can recognize the peptide and initiate an immune response. The H-2Kb molecule, found on the surface of many cells, displays intracellularly produced peptides to cytotoxic T lymphocytes (CTLs), also known as CD8+ T cells.

Key Characteristics and Properties:

* Sequence: Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu (SIINFEKL)

* Molecular Formula: C45H74N10O13

* CAS Numbers: Commonly associated with CAS No. 1262751-08-5 and 138831-86-4.

* Form: Often supplied as OVA Peptide (257-264) TFA, where TFA (trifluoroacetic acid) is used for purification and stabilization.

* Origin: Derived from ovalbumin, the main protein in egg whiteThis is aclass I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb..

Significance in Immunological Research

The primary utility of OVA Peptide (257-264) lies in its well-defined immunogenic properties, making it an invaluable tool for studying various aspects of cellular immunityOVA Peptide (257-264) | PEPTIDE INSTITUTE, INC..

* T-Cell Activation: OVA Peptide (257-264) is extensively used to stimulate T cells, particularly CD8+ T cells. This stimulation can lead to the proliferation and activation of cytotoxic T lymphocytes (CTLs), which are crucial for eliminating infected or cancerous cellsSIINFEKL sequence.OVA Peptide (257-264) is a fragment of the OVA protein that stimulates an antibody response. It has been shown to activate various types .... Researchers utilize this peptide to induce an immune response in animal models, allowing them to study the mechanisms of T-cell mediated immunity.

* Immunotherapy and Vaccine Development: The ability of OVA Peptide (257-264) to elicit a strong immune response makes it a candidate for use in developing immunotherapeutic vaccines. It can be employed to test the efficacy of new adjuvants, which are substances that enhance the immune response to an antigen. The OVA 257-264 scrambled (FILKSINE) variant is also used in such studies, providing a control to understand the specificity of the immune response.

* Understanding Antigen Presentation: As a model antigen, OVA Peptide (257-264) is instrumental in understanding how antigens are processed and presented by MHC class I molecules. Studies involving this ovalbumin-derived peptide help elucidate the interactions between peptides and MHC molecules, as well as the subsequent activation of T-cell receptors. The 25-D1.OVA peptide - MedchemExpress.com16 monoclonal antibody, for instance, is known to react specifically with the ovalbumin-derived peptide SIINFEKL bound to H-2Kb, highlighting its utility in specific immunological assays.

* Research-Grade Applications: Research-grade Ova 257 264 Peptide is readily available for various metabolic research studies and is a common component in peptide catalogs and peptide shops online.Genscript Corporation OVA Peptide (257-264) It is also offered by various suppliers as a peptide fragment or antigen peptide, often in quantities of 1 mg or more.

Variations and Related Concepts

While OVA Peptide (257-264) is the most commonly referenced, variations exist2023年12月11日—OVA Peptide(257-264) 是OVA 的I 类(Kb)-限制性肽表位，OVA 是由I 类MHC 分子H-2Kb 呈递的来自卵清蛋白的八聚体肽。. For example, OVA-G4 Peptide is a variant with the sequence SIIGFEKL, demonstrating how minor changes can affect peptide-antigen interactions. The broader concept of peptides encompasses a vast array of molecules with diverse functions, including those used in skincare for their purported skin-repairing benefits, though the peptide 257 discussed here is distinct from cosmetic peptides.OVA Peptide(257-264) (TFA) - MedChem Express

In summary, peptide 257, specifically OVA Peptide (257-264), is a well-characterized and essential tool in immunologyOVA Peptide(257-264) - TargetMol. Its role as a class I (Kb)-restricted peptide epitope of OVA presented by the H-2Kb molecule makes it a critical component for research into T-cell immunity, vaccine development, and antigen presentation mechanisms. Its availability as a research-grade Ova 257 264 Peptide ensures its continued use in advancing scientific understanding.